WWII was lost for all intents and purposes when Public Law 77-11, the Lend-Lease Act, was signed on 11 Mar 1941. After that, it was just a matter of time before the limited access to the natural resources need to fuel German industrial capability was swamped by the, for all practical purposes, unlimited access available to the US industrial base, which, BTW, was impervious to attack by the Axis powers. A second milestone in the path to victory was the establishment of the Persian Corridor and the deposing of the Shah in 1942 to ensure the path stayed open. The Arctic route to Murmansk/Archangel was open to attack by Germany naval forces and land-based aircraft. Even though the route Vladivostok accounted for over 50% of lendlease shipments to Russia, it was realitively open to interdiction by Japan (had Germany and Japan chosen to cooperate in the war against Russia). The route through Iran was out of the reach of both Japan and Germany.
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