Perhaps. I do not fully understand their agenda or allegiances, but there are militants in the Sinai who give the security apparatus problems. Cairo is different terrain though.
The Mubarak regime had a significant apparatus to watch and control those discontents, so I think it would be hard for any hardline, radical opponents to take action without it ratcheting up to pretty open conflicy very quickly. Egypt is not some burgeoning state. Its security forces would be fairly capable of controlling a critical situation unless you're talking about a very wide sort of insurgency, which I do not see this expanding to.
I will say this though...Egypt's current state of affairs is a complex problem and the issues are not black and white. What's even more interesting is the fact that you won't be able to pull tribal identity out of the average man on the street like you might an Afghan farmer from Helmand or Khandahar.
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