And, personally, I think the anti-Americanism is Pakistan is quite a bit different than that in Germany or South Korea.
Yes, it's much more intense - probably more intense than anywhere else in the world. However, I'd argue it will be much less so when the drone campaign eventually comes to an end and the American withdrawal from Afghanistan occurs - that is, once American policy stops impinging in the domestic Pakistani political sphere.

Actions matter. Pakistani anti-Americanism was less intense prior to 2001. Indonesian anti-Americanism, OTOH, was arguably much higher. These things can be managed, just as we've been managing them since 1945. The 'clash of civilizations' is a silly construct. Cultures differ, but they aren't going to inevitably clash.